CHANGES IN TYPE OF COLLAGEN DURING THE DEVELOPMENT OF HUMAN POST-BURN HYPERTROPHIC SCARS

被引：79

作者：

HAYAKAWA, T ^{[1
]}

HASHIMOTO, Y ^{[1
]}

MYOKEI, Y ^{[1
]}

AOYAMA, H ^{[1
]}

IZAWA, Y ^{[1
]}

机构：

[1] CHUKYO HOSP, DEPT PLAST SURG, NAGOYA 457, JAPAN

来源：

CLINICA CHIMICA ACTA | 1979年 / 93卷 / 01期

关键词：

D O I：

10.1016/0009-8981(79)90252-3

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Neutral-salt soluble collagen was relatively abundant in young post-burn hypertrophie scars. The content of insoluble collagen was fairly low in granulation tissues, whereas it gradually increased over 2 years and reached a significantly higher value than that in normal skins. Interrupted gel electrophoresis was carried out to estimate the relative proportions of type III and type I collagens in the pepsin digests of human normal skins and post-bum scars. Granulation tissues showed an abnormally higher ratio of type III to type I (0.37-0.72) than the mean value of normal skins (0.17 ± 0.04 (S.D.)). The ratio gradually decreased to the normal range after 2 years or so. © 1979.

引用

页码：119 / 125

页数：7

共 15 条

[1] CHARACTERIZATION OF COLLAGEN OF HUMAN HYPERTROPHIC AND NORMAL SCARS [J].