PREVALENCE OF HIV-INFECTION IN SERONEGATIVE HIGH-RISK INDIVIDUALS EXAMINED BY VIRUS ISOLATION AND PCR

被引：0

作者：

NIELSEN, C ^{[1
]}

TEGLBJAERG, LS ^{[1
]}

PEDERSEN, C ^{[1
]}

LUNDGREN, JD ^{[1
]}

NIELSEN, CM ^{[1
]}

VESTERGAARD, BF ^{[1
]}

机构：

[1] HVIDOVRE UNIV HOSP,DEPT INFECT DIS,COPENHAGEN,DENMARK

来源：

JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY | 1991年 / 4卷 / 11期

关键词：

HIV-1; ISOLATION; T4-CELLS; MACROPHAGES; POLYMERASE CHAIN REACTION; SERONEGATIVE; HIGH-RISK SEXUAL ACTIVITY;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

HIV seronegative individuals with high-risk behavior were tested for HIV infection by sensitive virus isolation techniques using T4 lymphocytes and monocyte/macrophages, and by detection of proviral DNA using PCR with three different sets of nested primers. No evidence of HIV infection was found among the 31 seronegative high-risk subjects, either by virus isolation of by PCR (97.5% confidence limits, 0-11). Our results indicate that ongoing HIV infection in seronegative persons at high risk of infection is a rare event.

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页码：1107 / 1111

页数：5

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