PROLACTIN RECEPTOR IN HUMAN MAMMARY-CARCINOMA

被引:25
作者
DICARLO, R
MUCCIOLI, G
机构
关键词
D O I
10.1177/030089167906500605
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The specific binding of labelled human prolactin was determined in 83 human breast carcinomas. 27 tumors (32.5%) contained specific binding for prolactin of at least 1% and were considered prolactin receptor positive. The binding was found linearly related to membrane protein concentration and specific only for lactogenic hormones. By Scatchard analysis the dissociation constant appeared similar to that observed in other target tisues, with a low binding capacity.
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页码:695 / 702
页数:8
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