DETECTION OF AN EPIMASTIGOTE-LIKE INTRACELLULAR STAGE OF TRYPANOSOMA-CRUZI

被引：42

作者：

FAUCHER, JF ^{[1
]}

BALTZ, T ^{[1
]}

PETRY, KG ^{[1
]}

机构：

[1] INSERM,U394,F-33077 BORDEAUX,FRANCE

来源：

PARASITOLOGY RESEARCH | 1995年 / 81卷 / 05期

关键词：

D O I：

10.1007/BF00931508

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Monoclonal antibody (mAb) DION 5.1b, derived from mice immunized with Trypanasoma dionisii, recognizes a 72/76-kD surface glycoprotein specific to the epimastigote stage of T. dionisii and T. cruzi. None of the three other stages of the T. cruzi life cycle expresses any DION 5.1b-specific epitope. However, mAb DION 5.1b labels an intracellular form with ''epimastigote-like'' morphology that appears to be late and transient in the intracellular cycle. This result suggests that the morphological similarity between the observed ''epimastigote-like'' intracellular form in mammals and the epimastigote form in insects may extend to the antigenic pattern.

引用

页码：441 / 443

页数：3

共 12 条

[1] DEVELOPMENTALLY REGULATED, PHOSPHOLIPASE-C MEDIATED RELEASE OF THE MAJOR SURFACE GLYCOPROTEIN OF AMASTIGOTES OF TRYPANOSOMA-CRUZI [J].