ANTIBIOTICS FROM BASIDIOMYCETES .9. OUDEMANSIN, AN ANTIFUNGAL ANTIBIOTIC FROM OUDEMANSIELLA-MUCIDA (SCHRADER EX FR) HOEHNEL (AGARICALES)

被引:119
作者
ANKE, T
HECHT, HJ
SCHRAMM, G
STEGLICH, W
机构
[1] UNIV WURZBURG,FORSCH RONTGENSTRUKT ANAL BIOL MAKROMOLEK GRP,D-8700 WURZBURG,FED REP GER
[2] UNIV BONN,INST ORGAN CHEM & BIOCHEM,D-5300 BONN 1,FED REP GER
关键词
D O I
10.7164/antibiotics.32.1112
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
From mycelial cultures of Oudemansiella mucida a crystalline optically active antibiotic, oudemansin (2), has been isolated; its structure is closely related to strobilurin A (1). The relative configuration of oudemansin have been determined by X-ray analysis. The antibiotic exhibits strong antifungal properties and inhibits respiration in fungi, cells of the ascitic form of Ehrlich carcinoma, and rat liver mitochondria. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码:1112 / 1117
页数:6
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