TISSUE AND SUBCELLULAR-DISTRIBUTION OF BOUND AND ACID-LABILE SULFUR, AND THE ENZYMATIC CAPACITY FOR SULFIDE PRODUCTION IN THE BAT

被引：0

作者：

OGASAWARA, Y ^{[1
]}

ISODA, S ^{[1
]}

TANABE, S ^{[1
]}

机构：

[1] MEIJI COLL PHARM, DEPT HYG CHEM, TANASHI, TOKYO 188, JAPAN

来源：

BIOLOGICAL & PHARMACEUTICAL BULLETIN | 1994年 / 17卷 / 12期

关键词：

BOUND SULFUR; DESULFURATION PATHWAY; DISTRIBUTION; ACID-LABILE SULFUR; GAMMA-CYSTATHIONASE; 3-MERCAPTOPYRUVATE SULFURTRANSFERASE;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The tissue and subcellular distribution in liver and kidney of bound and acid-labile sulfur as well as the enzyme capacity for sulfide production related to the desulfuration pathway were determined in rats. Bound sulfur was widely distributed in tissues and highest in kidney, whereas acid-labile sulfur was highest in heart. Bound sulfur was found primarily in the cytosolic fraction in the form of high molecular weight material in liver, and as both high and low molecular weight material in kidney. Acid-labile sulfur was located in the mitochondrical fraction. Sulfide production capacity from cysteine was greatest in liver cytosol. This capacity was well correlated with the distribution of gamma-cystathionase in tissues and subcellular fractions.

引用

页码：1535 / 1542

页数：8

共 28 条

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