YACS, BACS, PACS AND MACS - ARTIFICIAL CHROMOSOMES AS RESEARCH TOOLS

被引：106

作者：

MONACO, AP ^{[1
]}

LARIN, Z ^{[1
]}

机构：

[1] UNIV OXFORD,DEPT BIOCHEM,CRC,CHROMOSOME MOLEC BIOL GRP,OXFORD OX1 3QU,ENGLAND

来源：

TRENDS IN BIOTECHNOLOGY | 1994年 / 12卷 / 07期

关键词：

D O I：

10.1016/0167-7799(94)90140-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragments of DNA to be cloned. In order to overcome several disadvantages of YACs, including chimaerism and instability, several complementary bacterial artificial chromosome (BAC) vectors have been developed. More recently, attempts are being made to construct artificial chromosomes in mammalian cells (MACs).

引用

页码：280 / 286

页数：7

共 50 条

[1] MAPPING THE WHOLE HUMAN GENOME BY FINGERPRINTING YEAST ARTIFICIAL CHROMOSOMES [J].

BELLANNECHANTELOT, C ;

LACROIX, B ;

OUGEN, P ;

BILLAULT, A ;

BEAUFILS, S ;

BERTRAND, S ;

GEORGES, I ;

GLIBERT, F ;

GROS, I ;

LUCOTTE, G ;

SUSINI, L ;

CODANI, JJ ;

GESNOUIN, P ;

POOK, S ;

VAYSSEIX, G ;

LUKUO, J ;

RIED, T ;

WARD, D ;

CHUMAKOV, I ;

LEPASLIER, D ;

BARILLOT, E ;

COHEN, D .

CELL, 1992, 70 (06) :1059-1068

[2] ON THE NATURE OF ORIGINS OF DNA-REPLICATION IN EUKARYOTES [J].

BENBOW, RM ;

ZHAO, JY ;

LARSON, DD .

BIOESSAYS, 1992, 14 (10) :661-670

[3] Mammalian artificial chromosomes [J].

Brown, William R. A. .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1992, 2 (03) :479-486

[4] MOLECULAR-CLONING OF HUMAN TELOMERES IN YEAST [J].

BROWN, WRA .

NATURE, 1989, 338 (6218) :774-776

[5] CLONING OF LARGE SEGMENTS OF EXOGENOUS DNA INTO YEAST BY MEANS OF ARTIFICIAL CHROMOSOME VECTORS [J].

BURKE, DT ;

CARLE, GF ;

OLSON, MV .

SCIENCE, 1987, 236 (4803) :806-812

[6] CONTINUUM OF OVERLAPPING CLONES SPANNING THE ENTIRE HUMAN CHROMOSOME-21Q [J].

CHUMAKOV, I ;

RIGAULT, P ;

GUILLOU, S ;

OUGEN, P ;

BILLAUT, A ;

GUASCONI, G ;

GERVY, P ;

LEGALL, I ;

SOULARUE, P ;

GRINAS, L ;

BOUGUELERET, L ;

BELLANNECHANTELOT, C ;

LACROIX, B ;

BARILLOT, E ;

GESNOUIN, P ;

POOK, S ;

VAYSSEIX, G ;

FRELAT, G ;

SCHMITZ, A ;

SAMBUCY, JL ;

BOSCH, A ;

ESTIVILL, X ;

WEISSENBACH, J ;

VIGNAL, A ;

RIETHMAN, H ;

COX, D ;

PATTERSON, D ;

GARDINER, K ;

HATTORI, M ;

SAKAKI, Y ;

ICHIKAWA, H ;

OHKI, M ;

LEPASLIER, D ;

HEILIG, R ;

ANTONARAKIS, S ;

COHEN, D .

NATURE, 1992, 359 (6394) :380-387

[7] ISOLATION OF A YEAST CENTROMERE AND CONSTRUCTION OF FUNCTIONAL SMALL CIRCULAR CHROMOSOMES [J].

CLARKE, L ;

CARBON, J .

NATURE, 1980, 287 (5782) :504-509

[8] A 1ST-GENERATION PHYSICAL MAP OF THE HUMAN GENOME [J].

COHEN, D ;

CHUMAKOV, I ;

WEISSENBACH, J .

NATURE, 1993, 366 (6456) :698-701

[9] POSITIONAL CLONING - LETS NOT CALL IT REVERSE ANYMORE [J].

COLLINS, FS .

NATURE GENETICS, 1992, 1 (01) :3-6

[10] STRUCTURE OF THE PERICENTRIC LONG ARM REGION OF THE HUMAN Y-CHROMOSOME [J].

COOPER, KF ;

FISHER, RB ;

TYLERSMITH, C .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 228 (02) :421-432

← 1 2 3 4 5 →