IGE-POSITIVE EPIDERMAL LANGERHANS CELLS IN ALLERGIC CONTACT-DERMATITIS LESIONS PROVOKED IN PATIENTS WITH ATOPIC-DERMATITIS

被引：10
|
作者：
SUGIURA, H [1 ]
UEHARA, M [1 ]
MAEDA, T [1 ]
机构：
[1] SHIGA UNIV MED SCI,DEPT ANAT,OTSU,SHIGA 52021,JAPAN
来源：
ARCHIVES OF DERMATOLOGICAL RESEARCH | 1990年 / 282卷 / 05期
关键词：
Atopic dermatitis; Atopic respiratory disease; Dinitrochlorobenzene; IgE; Langerhans cells;
D O I：
10.1007/BF00375722
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
To see whether or not IgE-bearing epidermal Langerhans cells are specific to skin lesions of atopic dermatitis (AD), we performed immunohistochemical and immunoelectron microscopic examinations of dinitrochlorobenzene (DNCB) contact dermatitis lesions provoked in uninvolved skin of eight patients with AD. In all of the eight examined, IgE-positive epidermal Langerhans cells were observed in the DNCB dermatitis lesions. Typical staining of anti-IgE was absent in the epidermis of normal-appearing skin of five patients with AD. Thus, it is likely that IgE positive epidermal Langerhans cells non-specifically occur in different eczematous diseases provoked in patients with AD. © 1990 Springer-Verlag.
引用
收藏
页码：295 / 299
页数：5
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