BIOLOGICAL ACTION OF ULTRASOUND IN RELATION TO CELL CYCLE

被引:26
作者
CLARKE, PR
HILL, CR
机构
[1] Physics Department, Institute of Cancer Research, Belmont, Sutton, Surrey
关键词
D O I
10.1016/0014-4827(69)90529-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In a population of L 5178 Y mouse leukaemia cells exposed to continuous 1 MHz ultrasonic irradiation in aqueous suspension culture, cells which are in M during the irradiation are found to have a susceptibility to ultrasonic disintegration that is significantly above the average for the population. A fractional irradiation regime however, with ultrasound pulses sufficiently short (≤ 1 msec) that the disintegration mechanism is inhibited, does not lead to detectable changes in the cell proliferation pattern. © 1969.
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页码:443 / &
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