ANALYSIS OF ESOPHAGEAL STITCHES EFFICIENCY WITH BOERHAAVE SYNDROME (EXPERIMENTAL STUDY)

The experimental study was conducted in two stages: at the first stage modeling of Boerhaave syndrome was performed, at the second stage examination of strength of the stitches applied to the esophagus and histologic examination of the esophageal wall at various times after its rupture. The experiment was carried out using threemonth- old male rats with the weight of 265-285 grams as the study material. Original devices were developed for modeling of Boerhaave syndrome and esophagus stitch strength determination. The data obtained showed that after the esophagus wall rupture in the esophagus wall and surrounding tissues and chest organs, the inflammatory phenomena and bacterial load increase synchronously and progressively with the increase of the time interval that has passed since the moment of rupture. Which explains esophagus, lungs, and trachea inflammatory response and destruction. This proves experimentally that the main reason for the frequent failure of stitches among patients with the Boerhaave syndrome is the increase in infiltration and destructive changes in the esophageal wall, pleura and adjacent organs.