ANTINEOPLASTIC AGENTS .257. ISOLATION AND STRUCTURE OF SPONGISTATIN-1

被引：297

作者：

PETTIT, GR ^{[1
]}

CICHACZ, ZA ^{[1
]}

GAO, F ^{[1
]}

HERALD, CL ^{[1
]}

BOYD, MR ^{[1
]}

SCHMIDT, JM ^{[1
]}

HOOPER, JNA ^{[1
]}

机构：

[1] ARIZONA STATE UNIV,DEPT CHEM,TEMPE,AZ 85287

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 06期

关键词：

D O I：

10.1021/jo00058a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An Eastern Indian Ocean sponge in the genus Spongia contains a structurally unprecedented macrocyclic lactone, spongistatin 1 (3), with extremely potent activity against selected human tumor cell types in the U.S. National Cancer Institute's primary screen.

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收藏

页码：1302 / 1304

页数：3

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