Non-opioid analgesics: Novel approaches to perioperative analgesia for major spine surgery

被引：78

作者：

Dunn, Lauren K. ^{[1
]}

Durieux, Marcel E. ^{[1
,2
]}

Nemergut, Edward C. ^{[1
,2
]}

机构：

[1] Univ Virginia, Dept Anesthesiol, Charlottesville, VA 22903 USA

[2] Univ Virginia, Dept Neurosurg, Charlottesville, VA 22903 USA

来源：

BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY | 2016年 / 30卷 / 01期

关键词：

dexmedetomidine; gabapentin; ketamine; multimodal pain management; paracetamol; perioperative pain; postoperative pain; pregabalin;

D O I：

10.1016/j.bpa.2015.11.002

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Perioperative pain management is a significant challenge following major spine surgery. Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and neuropathic sources. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. Here we review the evidence supporting the use of novel analgesic approaches as an alternative to intravenous opioids for major spine surgery. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：79 / 89

页数：11

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