STRUCTURE OF FISCHERIN, A NEW TOXIC METABOLITE FROM AN ASCOMYCETE, NEOSARTORYA-FISCHERI VAR FISCHERI

被引:54
作者
FUJIMOTO, H [1 ]
IKEDA, M [1 ]
YAMAMOTO, K [1 ]
YAMAZAKI, M [1 ]
机构
[1] CHIBA UNIV,FAC PHARMACEUT SCI,1-33 YAYOI CHO,INAGE KU,CHIBA 263,JAPAN
来源
JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 08期
关键词
D O I
10.1021/np50098a010
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new toxic metabolite named fischerin [1] from an Ascomycete. Neosartorya fischeri var. fischeri, which caused lethal peritonitis in mice, was deduced to have a structure including a 1,4-dihydroxy-3,5-disubstituted-2(1H)-pyridone moiety by chemical and spectral data.
引用
收藏
页码:1268 / 1275
页数:8
相关论文
共 17 条
[1]   FUNICULOSIN, A NEW ANTIBIOTIC .2. STRUCTURE ELUCIDATION AND ANTIFUNGAL ACTIVITY [J].
ANDO, K ;
MATSUURA, I ;
NAWATA, Y ;
ENDO, H ;
SASAKI, H ;
OKYTOMI, T ;
SAEHI, T ;
TAMURA, G .
JOURNAL OF ANTIBIOTICS, 1978, 31 (06) :533-538
[2]   TRYPTOQUIVALINE AND TRYPTOQUIVALONE, 2 TREMORGENIC METABOLITES OF ASPERGILLUS-CLAVATUS [J].
CLARDY, J ;
SPRINGER, JP ;
BUCHI, G ;
MATSUO, K ;
WIGHTMAN, R .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (03) :663-665
[3]   C-13 MAGNETIC-RESONANCE .23. METHYLDECALINS/LI [J].
DALLING, DK ;
GRANT, DM ;
PAUL, EG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (11) :3718-3724
[4]   STRUCTURE AND BIOSYNTHESIS OF HARZIANOPYRIDONE, AN ANTIFUNGAL METABOLITE OF TRICHODERMA-HARZIANUM [J].
DICKINSON, JM ;
HANSON, JR ;
HITCHCOCK, PB ;
CLAYDON, N .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (11) :1885-1887
[5]  
Fujimoto H., 1988, Proceedings of the Japanese Association of Mycotoxicology, P15
[6]  
HORIE Y, 1981, T MYCOL SOC JPN, V22, P113
[7]  
HORIE Y, 1986, THESIS CHIBA U CHIBA, P16
[8]  
ISHII H, 1977, TETRAHEDRON LETT, P1227, DOI 10.1016/S0040-4039(01)92982-X
[9]  
LEETE E, 1975, TETRAHEDRON LETT, P4103
[10]  
MATSUMOTO M, 1976, TETRAHEDRON LETT, P3827