NEW STEMODANE DITERPENES FROM STEMODIA-MARITIMA

被引：24

作者：

HUFFORD, CD ^{[1
]}

OGUNTIMEIN, BO ^{[1
]}

MUHAMMAD, I ^{[1
]}

机构：

[1] UNIV MISSISSIPPI,SCH PHARM,PHARMACEUT SCI RES INST,UNIVERSITY,MS 38677

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 01期

关键词：

D O I：

10.1021/np50079a007

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

EtOH extraction of n-hexane defatted Stemodia maritima has yielded four new stemodane diterpenes after solvent partitions and chromatographic separations. These diterpenes have been identified as maristeminol {2} and stemodinosides A {3}, B {4}, and C {5} from C-13-nmr comparisons with stemodin {1}. The antiviral activity and cytotoxicity of these derivatives were tested, but they were essentially not active.

引用

页码：48 / 52

页数：5

共 8 条

[1] A SIMPLIFIED PLAQUE REDUCTION ASSAY FOR ANTIVIRAL AGENTS FROM PLANTS - DEMONSTRATION OF FREQUENT OCCURRENCE OF ANTIVIRAL ACTIVITY IN HIGHER-PLANTS [J].

ABOUKARAM, M ;

SHIER, WT .

JOURNAL OF NATURAL PRODUCTS, 1990, 53 (02) :340-344

[2] FURTHER STUDIES ON ASSIGNMENT OF SIGNALS IN C-13 MAGNETIC-RESONANCE SPECTRA OF ALDOSES AND DERIVED METHYL GLYCOSIDES [J].

GORIN, PAJ ;

MAZUREK, M .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (08) :1212-1223

[3] H-1-NMR AND C-13-NMR ASSIGNMENTS FOR THE STEMODIA DITERPENES, STEMODIN, STEMODINONE, AND MARITIMOL [J].

HUFFORD, CD .

JOURNAL OF NATURAL PRODUCTS, 1988, 51 (02) :367-369

[4] PREPARATION, CHARACTERIZATION, AND ANTIVIRAL ACTIVITY OF MICROBIAL METABOLITES OF STEMODIN [J].

HUFFORD, CD ;

BADRIA, FA ;

ABOUKARAM, M ;

SHIER, WT ;

ROGERS, RD .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (06) :1543-1552

[5] 2 NEW DITERPENES FROM STEMODIA-MARITIMA L [J].

HUFFORD, CD ;

GUERRERO, RO ;

DOORENBOS, NJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1976, 65 (05) :778-780

[6] TOTAL SYNTHESIS OF RACEMIC 2-DESOXYSTEMODINONE AND STEMODINOL - THE IDENTITY OF NATURAL STEMODINOL WITH STEMARIN [J].

KELLY, RB ;

HARLEY, ML ;

ALWARD, SJ ;

MANCHAND, PS .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1982, 60 (05) :675-677

[7] STRUCTURES OF STEMODIN AND STEMODINONE [J].

MANCHAND, PS ;

WHITE, JD ;

WRIGHT, H ;

CLARDY, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (08) :2705-2706

[8] X-RAY STRUCTURE AND ABSOLUTE STEREOCHEMISTRY OF STEMARIN, A DITERPENE WITH A NEW SKELETON [J].

MANCHAND, PS ;

BLOUNT, JF .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1975, (21) :894-895

← 1 →