3-DIMENSIONAL IMAGE OF TUBULIN IN ZINC-INDUCED SHEETS, RECONSTRUCTED FROM ELECTRON-MICROGRAPHS

被引：33

作者：

AMOS, LA ^{[1
]}

BAKER, TS ^{[1
]}

机构：

[1] BRANDEIS UNIV,ROSENSTIEL BAS MED SCI RES CTR,WALTHAM,MA 02154

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 1979年 / 1卷 / 04期

关键词：

D O I：

10.1016/0141-8130(79)90042-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A three-dimensional image of zinc-induced brain tubulin sheets has been reconstructed by computer from digitized electron microscope images of negatively stained specimens. Different views of the sheets were obtained by tilting the specimens in the microscope and also by sectioning normal to the plane of the sheets. The overall resolution of the data is about 2 nm. The features of the resulting three-dimensional model suggest an explanation for the somewhat variable appearance of tubulin subunits in electron microscope images of negatively stained intact and opened-out microtubules. © 1979.

引用

页码：146 / 156

页数：11

共 27 条

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