FAT-CELL SIZE AND LIPID-CONTENT OF SUBCUTANEOUS TISSUE IN CONGENITAL GENERALIZED LIPODYSTROPHY

被引：12
作者：
ROGNUM, TO
BJERVE, KS
SEIP, M
TRYGSTAD, O
OSEID, S
机构：
[1] UNIV OSLO, RIKSHOSP, PAEDIAT RES INST, OSLO, NORWAY
[2] UNIV OSLO, RIKSHOSP, INST CLIN BIOCHEM, OSLO, NORWAY
来源：
ACTA ENDOCRINOLOGICA | 1978年 / 88卷 / 01期
关键词：
D O I：
10.1530/acta.0.0880182
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Fat cell size and lipid composition of subcutaneous tissue from 3 patients with congenital generalized lipodystrophy have been measured before and after treatment with either pimozide, fenfluramine or hypophysectomy. The fat cell volume before treatment ranged between 9.8 x 104 and 17.7 x 104 μm3, compared to 9.0 x 104 and 85.3 x 104 μm3 in 15 controls. The amount of lipids was only 1/10 to 1/50 of normal, triglycerides being the most heavily reduced lipid component. Neither the fat cell size nor the lipid content were affected by treatment with hypophysectomy, pimozide or fenfluramine.
引用
收藏
页码：182 / 189
页数：8
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