LINKAGE MAPPING OF THE CARBONYL REDUCTASE (CBR) GENE ON HUMAN CHROMOSOME-21 USING A DNA POLYMORPHISM IN THE 3' UNTRANSLATED REGION

被引：14

作者：

AVRAMOPOULOS, D

COX, T

FORREST, GL

CHAKRAVARTI, A

ANTONARAKIS, SE

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,CTR MED GENET,DEPT PEDIAT & MED,BALTIMORE,MD 21205

[2] CITY HOPE NATL MED CTR,BECKMAN RES INST,DEPT BIOL,DUARTE,CA 91010

[3] UNIV PITTSBURGH,DEPT HUMAN GENET,PITTSBURGH,PA 15261

来源：

GENOMICS | 1992年 / 13卷 / 02期

关键词：

D O I：

10.1016/0888-7543(92)90268-W

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A DNA polymorphism has been found in the 3′ untranslated region of the carbonyl reductase gene (CBR). Genotypes of the members of the CEPH pedigrees have been obtained and used in linkage analysis to map the CBR gene in the linkage map of human chromosome 21. The gene maps between the interferon-α receptor (IFNAR) and the D21S55 loci. © 1992.

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收藏

页码：447 / 448

页数：2

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