LANTHANIDE COMPLEX-OLIGO-DNA HYBRID FOR SEQUENCE-SELECTIVE HYDROLYSIS OF RNA

被引：123

作者：

MATSUMURA, K ^{[1
]}

ENDO, M ^{[1
]}

KOMIYAMA, M ^{[1
]}

机构：

[1] UNIV TOKYO, FAC ENGN, DEPT CHEM & BIOTECHNOL, TOKYO 113, JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 17期

关键词：

D O I：

10.1039/c39940002019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iminodiacetate complexes of lanthanide(III) ions (lutetium, europium, thulium and lanthanum), attached to the 5'-end of a 15-mer DNA, hydrolyse a 39-mer RNA selectively at the 3'-side of its 15-mer sequence, which is complementary with the DNA.

引用

页码：2019 / 2020

页数：2

共 20 条

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