NEW ENTRY TO CHIRAL BASE CATALYST - ASYMMETRIC MICHAEL ADDITION OF ALPHA-SUBSTITUTED BETA-KETO-ESTERS TO METHYL VINYL KETONE CATALYZED BY PODAND-TYPE ALKALI-METAL 2'-SUBSTITUTED 1,1'-BINAPHTHALEN-2-OXIDES

被引：24

作者：

TAMAI, Y

KAMIFUKU, A

KOSHIISHI, E

MIYANO, S

机构：

来源：

CHEMISTRY LETTERS | 1995年 / 10期

关键词：

D O I：

10.1246/cl.1995.957

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric Michael reactions of alpha-substituted beta-keto esters with methyl vinyl ketone catalyzed by 10 mol% of sodium 2'-[2-(2-methoxyethoxy)ethoxy]-1,1'-binaphthalen-2-oxide gave the optically active adducts quantitatively in up to 64% enantiomeric excess.

引用

页码：957 / 958

页数：2

共 2 条

[1] Asymmetric Michael addition of 2-alkoxyphenyl α-substituted nitroacetates to non-prochiral α,β-unsaturated carbonyl compounds catalyzed by podand-type alkali metal 2′-substituted 1,1′-binaphthalen-2-oxides
Otani, Toyohiro
Sugawara, Aldfumi
Tamai, Yasufumi
TETRAHEDRON LETTERS, 2014, 55 (35) : 4923 - 4926
[2] Highly enantioselective Michael addition of 2-alkoxyphenyl esters of α-substituted β-keto acids to non-prochiral α,β-unsaturated carbonyl compounds catalyzed by sodium 2′-[2-(2-methoxyethoxy)ethoxy]-1,1′-binaphthalen-2-oxide
Otani, Toyohiro
Namatame, Wataru
Tamai, Yasufumi
TETRAHEDRON LETTERS, 2014, 55 (50) : 6943 - 6945

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