BIOSENSOR MONITORING OF BLOOD LACTATE DURING OPEN-HEART-SURGERY

被引：9

作者：

KYROLAINEN, M

HAKANSON, H

EKROTH, R

MATTIASSON, B

机构：

[1] Department of Biotechnology, Chemical Centre, Lund University, S-221 00 Lund

来源：

ANALYTICA CHIMICA ACTA | 1993年 / 279卷 / 01期

关键词：

BIOSENSORS; ENZYMATIC METHODS; BLOOD; ENZYME REACTOR; LACTATE; SURGERY;

D O I：

10.1016/0003-2670(93)85077-W

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An on-line monitoring system for lactate in blood is described. The system consists of a sampling unit allowing dilution at the sampling point, a sample treatment unit for dialysis of the sample and an enzyme reactor with immobilized lactate oxidase. A Clark electrode is used as transducer. The enzyme preparation shows high storage stability and good operational stability. The system was used, during and after open-heart surgery, to follow fluctuation in the concentrations Of L-lactate in blood being pumped to and from the brain. A small difference of approximately 0.3-0.5 mM was monitored.

引用

页码：149 / 153

页数：5

共 8 条

[1]

HAKANSON H, 1988, METHOD ENZYMOL, V137, P319

[2]

HAKANSON H, IN PRESS BIOSENSORS

[3]

MASCINI M, 1987, CLIN CHEM, V33, P591

[4]

PALLESCHI G, 1989, ANAL LETT, V22, P1209