IDENTIFICATION OF A NOVEL CONSERVED HUMAN GENE, TEGT

被引：33
|
作者：
WALTER, L
MARYNEN, P
SZPIRER, J
LEVAN, G
GUNTHER, E
机构：
[1] UNIV GOTTINGEN,DIV IMMUNOGENET,D-37073 GOTTINGEN,GERMANY
[2] UNIV LOUVAIN,CTR HUMAN GENET,LOUVAIN,BELGIUM
[3] FREE UNIV BRUSSELS,DEPT MOLEC BIOL,BRUSSELS,BELGIUM
[4] GOTHENBURG UNIV,DEPT GENET,GOTHENBURG,SWEDEN
来源：
GENOMICS | 1995年 / 28卷 / 02期
关键词：
D O I：
10.1006/geno.1995.1145
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A novel gene, TEGT (testis enhanced gene transcript), has been identified in humans. It does not belong to any known gene family of vertebrates. The deduced amino acid sequence of the gene and a bacterial protein of unknown function show low but significant homology and very similar hydrophobicity profiles. Two different transcripts of TEGT occur, which are due to alternative usage of two polyadenylation sites. The presence of a nuclear targeting motif indicates that the gene product might localize to the nucleus. The TEGT gene maps to human chromosome 12q12-q13 and belongs to a syntenic group, which is conserved in human, mouse, and rat. (C) 1995 Academic Press, Inc.
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收藏
页码：301 / 304
页数：4
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