BETA-CARBOLINE ALKALOIDS .2. TRIBUTYL(1-ETHOXYVINYL)STANNANE AS A C2-BUILDING BLOCK IN THE SYNTHESES OF BETA-CARBOLINE ALKALOIDS

被引：0

作者：

BRACHER, F ^{[1
]}

HILDEBRAND, D ^{[1
]}

机构：

[1] UNIV MARBURG,INST PHARMAZEUT CHEM,D-35037 MARBURG,GERMANY

来源：

LIEBIGS ANNALEN DER CHEMIE | 1993年 / 08期

关键词：

BETA-CARBOLINES; ALKALOIDS; ANNOMONTINE; NITRAMARINE; STANNANES; TIN COMPOUNDS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Acetyl-beta-carboline (4) is prepared by palladium-catalyzed coupling of 1-chloro-beta-carboline (1) with tributyl(l-ethoxyvinyl)stannane (3) and subsequent hydrolysis with aqueous acid. Reduction of 4 with NaBH4 gives the alkaloid 5. Nitra-marine (7) and annomontine (9) are prepared from 4 by one-pot conversions of the acetyl group to a quinoline or an aminopyrimidine ring, respectively.

引用

页码：837 / 839

页数：3

共 14 条

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