DIFFERENTIATION OF ALPHA-ADRENERGIC RECEPTORS USING PHARMACOLOGICAL EVALUATION AND MOLECULAR MODELING OF SELECTIVE ADRENERGIC AGENTS

被引：16
作者：
HANCOCK, AA
KYNCL, JJ
MARTIN, YC
DEBERNARDIS, JF
机构：
来源：
JOURNAL OF RECEPTOR RESEARCH | 1988年 / 8卷 / 1-4期
关键词：
D O I：
10.3109/10799898809048976
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
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页码：23 / 46
页数：24
相关论文
共 23 条
[1]   A STUDY OF THE ADRENOTROPIC RECEPTORS [J].
AHLQUIST, RP .
AMERICAN JOURNAL OF PHYSIOLOGY, 1948, 153 (03) :586-600
[2]   COMPUTER-ASSISTED INVESTIGATION OF STRUCTURE ACTIVITY RELATIONSHIP IN ALPHA-2-ADRENOCEPTOR LIGANDS [J].
BOVY, P ;
DEPRIJCK, A ;
DURANT, F .
JOURNAL OF MOLECULAR GRAPHICS, 1986, 4 (04) :234-234
[3]   CONFORMATIONALLY DEFINED ADRENERGIC AGENTS .4. 1-(AMINOMETHYL)PHTHALANS - SYNTHESIS AND PHARMACOLOGICAL CONSEQUENCES OF THE PHTHALAN RING OXYGEN ATOM [J].
DEBERNARDIS, JF ;
ARENDSEN, DL ;
KYNCL, JJ ;
KERKMAN, DJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (01) :178-184
[4]   CONFORMATIONALLY DEFINED ADRENERGIC AGENTS .1. DESIGN AND SYNTHESIS OF NOVEL ALPHA-2 SELECTIVE ADRENERGIC AGENTS - ELECTROSTATIC REPULSION BASED CONFORMATIONAL PROTOTYPES [J].
DEBERNARDIS, JF ;
KERKMAN, DJ ;
WINN, M ;
BUSH, EN ;
ARENDSEN, DL ;
MCCLELLAN, WJ ;
KYNCL, JJ ;
BASHA, FZ .
JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (10) :1398-1404
[5]   CONFORMATIONALLY DEFINED ADRENERGIC AGENTS .2. CATECHOL IMIDAZOLINE DERIVATIVES - BIOLOGICAL EFFECTS OF ALPHA-1 AND ALPHA-2 ADRENERGIC-RECEPTORS [J].
DEBERNARDIS, JF ;
KYNCL, JJ ;
BASHA, FZ ;
ARENDSEN, DL ;
MARTIN, YC ;
WINN, M ;
KERKMAN, DJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :463-467
[6]  
DEBERNARDIS JF, 1987, IN PRESS J MED CHEM
[7]  
DEBERNARDIS JF, 1986, Patent No. 4618683
[8]   SELECTIVITY OF BLOCKING-AGENTS FOR PRESYNAPTIC AND POSTSYNAPTIC ALPHA-ADRENOCEPTORS [J].
DOXEY, JC ;
SMITH, CFC ;
WALKER, JM .
BRITISH JOURNAL OF PHARMACOLOGY, 1977, 60 (01) :91-96
[9]   BINDING CHARACTERISTICS OF PRAZOSIN-H-3 TO RAT-BRAIN ALPHA-ADRENERGIC RECEPTORS [J].
GREENGRASS, P ;
BREMNER, R .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1979, 55 (03) :323-326
[10]  
HANCOCK AA, 1979, MOL PHARMACOL, V16, P1
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