MECHANISM OF THE POSTRECEPTOR DEFECT IN INSULIN ACTION IN HUMAN OBESITY - DECREASE IN GLUCOSE-TRANSPORT SYSTEM ACTIVITY

被引：112

作者：

CIARALDI, TP ^{[1
]}

KOLTERMAN, OG ^{[1
]}

OLEFSKY, JM ^{[1
]}

机构：

[1] UNIV COLORADO,HLTH SCI CTR,DEPT MED,DIV ENDOCRINOL METAB,DENVER,CO 80262

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1981年 / 68卷 / 04期

关键词：

D O I：

10.1172/JCI110342

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：875 / 880

页数：6

共 19 条

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[2]

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[3] MONOIODOINSULIN - DEMONSTRATION OF ITS BIOLOGICAL ACTIVITY AND BINDING TO FAT CELLS AND LIVER MEMBRANES [J].

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[5] CORRELATION BETWEEN INSULIN RECEPTOR-BINDING IN ISOLATED FAT-CELLS AND INSULIN SENSITIVITY IN OBESE HUMAN SUBJECTS [J].

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[7]

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[8] MECHANISMS OF INSULIN RESISTANCE IN HUMAN OBESITY - EVIDENCE FOR RECEPTOR AND POSTRECEPTOR DEFECTS [J].

KOLTERMAN, OG ;

INSEL, J ;

SAEKOW, M ;

OLEFSKY, JM .

JOURNAL OF CLINICAL INVESTIGATION, 1980, 65 (06) :1272-1284

[9] RELATIONSHIP BETWEEN INVIVO INSULIN RESISTANCE AND DECREASED INSULIN RECEPTORS IN OBESE MAN [J].

KOLTERMAN, OG ;

REAVEN, GM ;

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[10]

KONO T, 1971, J BIOL CHEM, V246, P6210

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