A STUDY OF SHEAR AND COMPRESSION DEFORMATIONS ON HYDROPHILIC GELS OF ALPHA-TOCOPHEROL

被引：4
作者：
LUCERO, MJ
VIGO, J
LEON, MJ
机构：
[1] Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Sevilla, 41012 Sevilla, C / Profesor Garcia Gonzalez, s/n
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1994年 / 111卷 / 03期
关键词：
SHEAR DEFORMATION; COMPRESSION DEFORMATION; PH; ALPHA-TOCOPHEROL; ASCORBIC ACID; CARBOMER(R) 940;
D O I：
10.1016/0378-5173(94)90349-2
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A rheological study of hydrophilic gels of Carbomer(R) 940 with alpha-tocopherol as drug, and ascorbic acid as antioxidant, has been carried out. At the same time, the effect of storage time has been determined. Both shear and compression deformations were applied. From the results obtained, correlations between both types of deformation have been established. The results were statistically significant between shear and compression stresses, and between shear stress and area of spreading.
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收藏
页码：261 / 269
页数：9
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