WATCHING FAT DIGESTION

被引:324
作者
PATTON, JS
CAREY, MC
机构
[1] Department of Medicine, Harvard Medical School, Peter Bent Brigham Hospital, Boston
关键词
D O I
10.1126/science.432636
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
During fat digestion a number of physicochemical events can be seen directly by light microscopy. Under simulated physiological conditions, hydrolysis of emulsified fat droplets by human pancreatic lipase in the presence of colipase and bile salt micelles proceeds with the sequential formation of 2 visible product phases. A lamellar liquid crystalline or crystalline phase containing calcium and ionized fatty acid forms first. This is followed by the production of a viscous isotropic phase composed predominantly of monoglycerides and protonated fatty acids.
引用
收藏
页码:145 / 148
页数:4
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