Perioperative antibiotic prophylaxis in gynecology. Problem of increasing colonization with resistant bacteria

被引：0

作者：

Hof H. ^{[1
]}

Oberdorfer K. ^{[1
]}

Schütt S. ^{[1
]}

Holfelder M. ^{[1
]}

Wendt C. ^{[1
]}

机构：

[1] MVZ Labor Dr. Limbach und Kollegen, 69126 Heidelberg

来源：

Der Gynäkologe | 2012年 / 45卷 / 11期

关键词：

Antibiotics; Enterobacteriaceae; Perioperative prophylaxis; Resistant bacteria; Wound infection;

D O I：

10.1007/s00129-012-3081-y

中图分类号：

学科分类号：

摘要：

The colonization of patients with resistant bacteria, such as methicillin resistant Staphylococcus aureus (MRSA), vancomycin resistant enterococci (VRE) and multiresistant enterobacteriaceae including the extended spectrum β-lactamase (ESBL) producing Gram negative bacteria, has reached considerable proportions especially among risk populations, such as the elderly, persons with frequent hospitalization episodes and immigrants. Whereas the prevalence of MRSA colonization has been decreasing in the last few years, the numbers of patients colonized with VRE or multiresistant enterobacteriaceae is still increasing. Cephalosporins of the second generation, such as cefazolin and cefuroxime, which are generally used for perioperative prophylaxis, are definitely not appropriate to prevent postoperative wound infections or even more severe complications in such situations. Hence, according to the given situation a targeted selection of the correct antibiotic from a large list of available agents is required to optimize the results of this preventive measurement. © Springer-Verlag Berlin Heidelberg 2012.

引用

页码：893 / 898

页数：5