A RAPID TEST FOR MEASURING THE INFECTIVITY OF YELLOW-FEVER VACCINE

被引:6
作者
SOOD, DK [1 ]
AGGARWAL, RK [1 ]
KUMAR, S [1 ]
SOKHEY, J [1 ]
机构
[1] NATL INST COMMUNICABLE DIS,NEW DELHI 110054,INDIA
关键词
YELLOW FEVER VACCINE; MOUSE LD(50); CCID50;
D O I
10.1016/0264-410X(94)00035-L
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
An in-house reference preparation of 170-204 Yellow Fever vaccine was tested 60 times using LD(50) mouse assay and CCID50 method. The mean virus titre, standard deviation and coefficient of variation obtained were comparable. Student's t-test indicated that there was a statistically insignificant difference between the two methods (p>0.05) used for potency test with a correlation coefficient of 0.666 (p<0.05), CCID50 assay for measuring the infectivity, of Yellow Fever vaccine is rapid sensitive and reproducible.
引用
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页码:427 / 428
页数:2
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