Antiaggregatory Effects Of Blood Vessels On Blood Neutrophils In Patients With Dyslipidemia

被引:0
作者
Medvedev, I. N. [1 ]
机构
[1] Russian State Social Univ, St V Pika 4, Moscow 129226, Russia
来源
RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES | 2018年 / 9卷 / 04期
关键词
neutrophils; pathology; dislipidemia; vascular wall; antiaggregation;
D O I
暂无
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Improving the quality and quantity of nutrition in modern society is accompanied by the preservation of the widespread prevalence of dyslipidemia among the population of industrially developed countries. Modern researchers associate the frequent occurrence of thrombosis of various localizations in dyslipidemia with impaired vascular function, especially in terms of their control over shaped elements. the goal is to establish the features of the disaggregation capabilities of blood vessels over neutrophils in patients with dyslipidemia. We examined 41 patients of the second mature age (mean age 53.8 +/- 1.6 years) with dislipidemia of Ilb type. The control group was composed of 26 clinically healthy people of the same age. All the examined persons gave written informed consent on participation in the research. There were applied biochemical, hematological and statistical methods of investigation. High thromboses' frequency of various localizations at arterial hypertension with dislipidemia is closely connected with angiopathy development against their background. Weakening of plasma antioxidant protection with activation of lipids' peroxidation processes in it leading to alteration of vascular wall, is noted in conditions of dislipidemia. The persons with arterial hypertension and dislipidemia are detected to have evident weakening of disaggregating vascular impacts of vascular wall on strengthening aggregative ability of neutrophils. In the result of it given patients get sharply increased risk of thromboses of any localization which can lead to invalidism and lethal outcome.
引用
收藏
页码:631 / 636
页数:6
相关论文
共 34 条
[1]  
Anatolyevich VY, 2017, BALI MED J, V6, P216, DOI 10.15562/bmj.v6i1.483
[2]  
[Anonymous], 2012, CARDIOVASCULAR THERA, V4, P31
[3]  
Apanasyuk LA, 2017, SCI NOTES RUSSIAN ST, V16, P143, DOI [10.17922/2071-5323-2017-16-5-143-150, DOI 10.17922/2071-5323-2017-16-5-143-150]
[4]  
Bikbulatova AA, 2018, RES J PHARM BIOL CHE, V9, P663
[5]  
Bikbulatova AA, 2018, RES J PHARM BIOL CHE, V9, P1417
[6]   Technique for Measuring Vocational Interests and Inclinations in High-School Students with Disabilities [J].
Bikbulatova, A. A. ;
Karplyuk, A. A. ;
Parshin, G. N. ;
Dzhafar-Zade, D. A. ;
Serebryakov, A. G. .
PSIKHOLOGICHESKAYA NAUKA I OBRAZOVANIE-PSYCHOLOGICAL SCIENCE AND EDUCATION, 2018, 23 (02) :50-58
[7]  
Bikbulatova AA, 2017, Psikhol Nauk Obrazov, V22, P26, DOI 10.17759/pse.2017220105
[8]  
Bikbulatova AA, 2017, Psikhol Nauk Obrazov, V22, P81, DOI 10.17759/pse.2017220110
[9]  
Diagnosis and treatment of hypertension, 2010, NATL CLIN RECOMMENDA, P463
[10]  
Gurevich VS., 2013, SYSTEMIC HYPERTENSIO, V3, P54