HYDRIDE TRANSFER VERSUS ELECTRON-TRANSFER IN THE BAKERS-YEAST REDUCTION OF ALPHA-HALOACETOPHENONES

被引：20

作者：

ALEIXO, LM ^{[1
]}

DECARVALHO, M ^{[1
]}

MORAN, PJS ^{[1
]}

RODRIGUES, JAR ^{[1
]}

机构：

[1] UNIV ESTADUAL CAMPINAS,INST QUIM,BR-13081 CAMPINAS,SP,BRAZIL

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 08期

关键词：

D O I：

10.1016/S0960-894X(00)80033-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The baker's yeast reduction of alpha-iodoacetophenone gave acetophenone. Some evidence for a free radical chain process in this reduction was obtained by addition of DNB which not only provoked a decrease in the formation of acetophenone but also allow the appearance of the enzyme-controlled formation of (-)-(R)-2-iodo-1-phenylethanol.

引用

页码：1637 / 1642

页数：6

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