ion channels;
mechanosensing;
mechanotransduction;
D O I:
10.3934/biophy.2016.1.63
中图分类号:
Q6 [生物物理学];
学科分类号:
071011 ;
摘要:
Cell surface receptors are involved in numerous important biological processes including embryogenesis, tissue differentiation, and cellular homeostasis. Among them, mechanosensitive ion channels play an essential role in cellular functions of every cell including neurons, cardiomyocytes, and osteocytes. Here, we discuss types, roles, structures, and biophysical factors that affect the functions of mechanosensitive ion channels.
机构:
Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Mol & Integrat Physiol, Ann Arbor, MI 48109 USAUniv Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
机构:
Univ Calif San Francisco, Sch Med, Dept Cellular & Mol Pharmacol, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Cellular & Mol Pharmacol, San Francisco, CA 94143 USA
机构:
Univ Western Australia, QEII Med Ctr, Sch Med & Pharmacol, Crawley, WA 6009, AustraliaUniv Western Australia, QEII Med Ctr, Sch Med & Pharmacol, Crawley, WA 6009, Australia
机构:
Life Sciences Institute and Department of Molecular and Integrative Physiology,University of MichiganLife Sciences Institute and Department of Molecular and Integrative Physiology,University of Michigan