A COMPLEX PYRROLO-OXAZINONE AND ITS IODO DERIVATIVE ISOLATED FROM A TUNICATE

被引：87

作者：

YOSHIDA, WY ^{[1
]}

LEE, KK ^{[1
]}

CARROLL, AR ^{[1
]}

SCHEUER, PJ ^{[1
]}

机构：

[1] UNIV HAWAII,DEPT CHEM,2545 THE MALL,HONOLULU,HI 96822

来源：

HELVETICA CHIMICA ACTA | 1992年 / 75卷 / 05期

关键词：

D O I：

10.1002/hlca.19920750525

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two cytotoxic triphenylpyrrolo-oxazinones were isolated from a tunicate and their structures elucidated by spectral methods. Lukianol A (= 3,7,8-tris(4-hydroxyphenyl)pyrrolo[2,1-c][1,4]oxazin-1 (1H)-one; 1) had MIC of 1-mu-g/ml in KB cytotoxicity tests; MIC value for 2 was 100-mu-g/ml.

引用

页码：1721 / 1725

页数：5

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