ISOLATION OF FACTOR-IX CONCENTRATE FROM DONORS PLASMA CRYOSUPERNATANT

被引:0
作者
FETISOVA, LV
VYAZOVA, EP
KHAMETOVA, RN
SHUVALOVA, AL
AZHIDIROVA, MA
LAZAREV, VA
ZEINALOV, AM
机构
来源
GEMATOLOGIYA I TRANSFUZIOLOGIYA | 1991年 / 36卷 / 06期
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Soviet anion-exchangers were comparatively studied to specify an optimal carrier useful for isolation of factor ix of the blood coagulation system from donor's blood cryosupernatant. The main criteria of gel selection were the yield and purification degree of factor IX, as well as its specific activity and concentration in eluates. It has been shown that DEAE-agarose 6B-CL, possessing pronounced activity with respect to specific sorption of factor IX, meets these requirements to the greatest degree.
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页码:34 / 36
页数:3
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