Mammalian artificial chromosomes

被引：26

作者：

Brown, William R. A. ^{[1
]}

机构：

[1] Univ Oxford, Biochem Dept, South Parks Rd, Oxford OX1 3QU, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(05)80161-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A mammalian artificial chromosome would enable analysis of the cis-acting DNA sequences necessary for mammalian chromosome function and would allow large numbers of genes in a defined sequence environment to be introduced into experimental animals, agricultural livestock or human cells. Recent technical progress suggests that a route to mammalian artifical chromosome construction is now open.

引用

页码：479 / 486

页数：8

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