A RAPID SOLID-PHASE METHOD FOR THE SYNTHESIS OF 3'-THIOL GROUP CONTAINING OLIGONUCLEOTIDES

被引：8

作者：

KUMAR, A

机构：

[1] National Institute of Immunology, Aruna Asaf A1i Marg, New Delhi

来源：

NUCLEOSIDES & NUCLEOTIDES | 1993年 / 12卷 / 07期

关键词：

D O I：

10.1080/07328319308021506

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid solid phase method for the synthesis of 3'-thiol group containing oligonucleotides is described.

引用

收藏

页码：729 / 736

页数：8

相关论文

共 27 条

[1] AGGARWAL S, 1986, NUCLEIC ACIDS RES, V14, P6227
[2] ANSORGE W, 1984, BIOCH BIOPHYS METHOD, V9, P3347
[3] SOLID-PHASE SYNTHESIS OF 5',3'-BIFUNCTIONAL OLIGODEOXYRIBONUCLEOTIDES BEARING A MASKED THIOL-GROUP AT THE 3'-END
BONFILS, E
THUONG, NT
[J]. TETRAHEDRON LETTERS, 1991, 32 (26) : 3053 - 3056
[4] BIOTIN-LABELED SYNTHETIC OLIGODEOXYRIBONUCLEOTIDES - CHEMICAL SYNTHESIS AND USES AS HYBRIDIZATION PROBES
CHOLLET, A
KAWASHIMA, EH
[J]. NUCLEIC ACIDS RESEARCH, 1985, 13 (05) : 1529 - 1541
[5] DERIVATIZATION OF UNPROTECTED POLYNUCLEOTIDES
CHU, BCF
WAHL, GM
ORGEL, LE
[J]. NUCLEIC ACIDS RESEARCH, 1983, 11 (18) : 6513 - 6529
[6] CHU BCF, 1991, DNA CELL BIOL, V14, P327
[7] THE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING A PRIMARY AMINO GROUP AT THE 5'-TERMINUS
CONNOLLY, BA
[J]. NUCLEIC ACIDS RESEARCH, 1987, 15 (07) : 3131 - 3139
[8] CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING A FREE SULFHYDRYL-GROUP AND SUBSEQUENT ATTACHMENT OF THIOL SPECIFIC PROBES
CONNOLLY, BA
RIDER, P
[J]. NUCLEIC ACIDS RESEARCH, 1985, 13 (12) : 4485 - 4502
[9] A NOVEL METHOD FOR THE INTRODUCTION OF AN ALIPHATIC PRIMARY AMINO GROUP AT THE 5' TERMINUS OF SYNTHETIC OLIGONUCLEOTIDES
COULL, JM
WEITH, HL
BISCHOFF, R
[J]. TETRAHEDRON LETTERS, 1986, 27 (34) : 3991 - 3994
[10] TISSUE SULFHYDRYL GROUPS
ELLMAN, GL
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) : 70 - 77