THE DISCOVERY AND DEVELOPMENT OF HMG-COA REDUCTASE INHIBITORS

[1] ALBERTS A W, 1988, Cahiers de Nutrition et de Dietetique, V23, P231

[2] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 3957 - 3961

[3] INFLUENCE OF NICOTINIC ACID ON SERUM CHOLESTEROL IN MAN [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1955, 54 (02) : 558 - 559

[4] ANGERBAUER R, 1992, 11 INT S DRUGS AFF L

[5] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NEW HMG-COA REDUCTASE INHIBITORS .1. LACTONES OF PYRIDINE-SUBSTITUTED AND PYRIMIDINE-SUBSTITUTED 3,5-DIHYDROXY-6-HEPTENOIC (-HEPTANOIC) ACIDS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (01) : 52 - 60

[6] INCORPORATION OF A PRODUCT OF MEVALONIC ACID METABOLISM INTO PROTEINS OF CHINESE-HAMSTER OVARY CELL-NUCLEI [J]. JOURNAL OF CELL BIOLOGY, 1988, 107 (04) : 1307 - 1316

[7] MEVINOLIN AND COLESTIPOL STIMULATE RECEPTOR-MEDIATED CLEARANCE OF LOW-DENSITY LIPOPROTEIN FROM PLASMA IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13): : 4124 - 4128

[8] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11): : 1165 - 1173

[9] REGRESSION OF CORONARY-ARTERY DISEASE AS A RESULT OF INTENSIVE LIPID-LOWERING THERAPY IN MEN WITH HIGH-LEVELS OF APOLIPOPROTEIN-B [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (19) : 1289 - 1298

[10] REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY IN HUMAN FIBROBLASTS BY LIPOPROTEINS [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (07) : 2162 - 2166

[1] ALBERTS A W, 1988, Cahiers de Nutrition et de Dietetique, V23, P231

[2] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 3957 - 3961

[3] INFLUENCE OF NICOTINIC ACID ON SERUM CHOLESTEROL IN MAN [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1955, 54 (02) : 558 - 559

[4] ANGERBAUER R, 1992, 11 INT S DRUGS AFF L

[5] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NEW HMG-COA REDUCTASE INHIBITORS .1. LACTONES OF PYRIDINE-SUBSTITUTED AND PYRIMIDINE-SUBSTITUTED 3,5-DIHYDROXY-6-HEPTENOIC (-HEPTANOIC) ACIDS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (01) : 52 - 60

[6] INCORPORATION OF A PRODUCT OF MEVALONIC ACID METABOLISM INTO PROTEINS OF CHINESE-HAMSTER OVARY CELL-NUCLEI [J]. JOURNAL OF CELL BIOLOGY, 1988, 107 (04) : 1307 - 1316

[7] MEVINOLIN AND COLESTIPOL STIMULATE RECEPTOR-MEDIATED CLEARANCE OF LOW-DENSITY LIPOPROTEIN FROM PLASMA IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13): : 4124 - 4128

[8] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11): : 1165 - 1173

[9] REGRESSION OF CORONARY-ARTERY DISEASE AS A RESULT OF INTENSIVE LIPID-LOWERING THERAPY IN MEN WITH HIGH-LEVELS OF APOLIPOPROTEIN-B [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (19) : 1289 - 1298

[10] REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY IN HUMAN FIBROBLASTS BY LIPOPROTEINS [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (07) : 2162 - 2166