A FOLLOW-UP-STUDY OF METHODS OF CONTRACEPTION, SEXUAL-ACTIVITY, AND RATES OF TRICHOMONIASIS, CANDIDIASIS, AND BACTERIAL VAGINOSIS

被引:135
作者
BARBONE, F [1 ]
AUSTIN, H [1 ]
LOUV, WC [1 ]
ALEXANDER, WJ [1 ]
机构
[1] UNIV ALABAMA,SCH PUBL HLTH,DEPT EPIDEMIOL,BIRMINGHAM,AL
关键词
bacterial vaginosis; candidiasis; oral contraceptives; spermicide; Trichomoniasis;
D O I
10.1016/0002-9378(90)91186-G
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A randomized, clinical trial was conducted to evaluate the spermicidal agent nonoxynol 9 as prophylaxis for sexually transmitted diseases. Eight hundred eighteen women using birth control who attended a sexually transmitted disease clinic were evaluated monthly for trichomoniasis, candidiasis, and bacterial vaginosis for 6 months. Women using the active spermicide experienced a somewhat lower incidence rate of trichomoniasis (relative rate 0.83; 95% confidence interval 0.61 to 1.12) and bacterial vaginosis (relative rate 0.86; 95% confidence interval 0.69 to 1.12) as compared with placebo users. The rate of candidiasis was nearly identical for spermicide and placebo users (relative rate 1.02; 95% confidence interval 0.77 to 1.35). The number of sexual partners during the preceding month was related directly to the occurrence of trichomoniasis (p = 0.047) and bacterial vaginosis (p = 0.009) but not candidiasis (p = 0.99). Subjects using oral contraceptives experienced a statistically significant lower rate of trichomoniasis than did women using an intrauterine contraceptive device or who had had a tubal ligation (relative rate 0.56; 95% confidence interval 0.39 to 0.81). © 1990.
引用
收藏
页码:510 / 514
页数:5
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