ENANTIOSELECTIVE SYNTHESIS USING CRUDE ENZYMES

被引：12

作者：

BASAVAIAH, D

KRISHNA, PR

机构：

[1] School of Chemistry, University of Hyderabad

来源：

PURE AND APPLIED CHEMISTRY | 1992年 / 64卷 / 08期

关键词：

D O I：

10.1351/pac199264081067

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral trans-2-aryloxycyclohexan-1-ols, trans-2-alkoxy cyclohexan-1-ols, trans-2-arylcyclohexan-1-ols, homoallyl alcohols, 1-aryl-1-alkanols, 1,2-diphenylethane-1,2-diol are prepared in high optical purities via enantioselective hydrolysis of acetates of the corresponding racemic alcohols using crude enzymes such as pig liver acetone powder (PLAP), goat liver acetone powder (GLAP), chicken liver acetone powder (CLAP) and bovine liver acetone powder (BLAP).

引用

收藏

页码：1067 / 1072

页数：6

相关论文

共 18 条

[1] ENANTIOSELECTIVE HYDROLYSIS OF RACEMIC ACETATES OF HOMOALLYL ALCOHOLS BY CRUDE PIG-LIVER ACETONE POWDER (PLAP) [J].

BASAVAIAH, D ;

RAO, PD .

SYNTHETIC COMMUNICATIONS, 1990, 20 (19) :2945-2949

[2] CONVENIENT ENANTIOSELECTIVE HYDROLYSIS OF RACEMIC TRANS-1-ACETOXY-2-ARYLOXYCYCLOHEXANES BY CRUDE PIG-LIVER ACETONE POWDER (PLAP) [J].

BASAVAIAH, D ;

KRISHNA, PR ;

BHARATHI, TK .

TETRAHEDRON LETTERS, 1990, 31 (30) :4347-4348

[3] SYNTHESIS OF CHIRAL 1-ARYLALKAN-1-OLS USING CRUDE ENZYMES [J].

BASAVAIAH, D ;

RAJU, SB .

SYNTHETIC COMMUNICATIONS, 1991, 21 (18-19) :1859-1863

[4]

BASAVAIAH D, UNPUB

[5] ORGANIC-CHEMISTRY - SYNTHESIS WITH A STRONG HAND [J].

BROWN, JM .

NATURE, 1991, 350 (6315) :191-191

[6] ASYMMETRIC APPROACH TO PAUSON-KHAND BICYCLIZATION - ENANTIOSELECTIVE FORMAL SYNTHESIS OF HIRSUTENE [J].

CASTRO, J ;

SORENSEN, H ;

RIERA, A ;

MORIN, C ;

MOYANO, A ;

PERICAS, MA ;

GREENE, AE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (25) :9388-9389

[7] GENERAL-ASPECTS AND OPTIMIZATION OF ENANTIOSELECTIVE BIOCATALYSIS IN ORGANIC-SOLVENTS - THE USE OF LIPASES [J].

CHEN, CS ;

SIH, CJ .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1989, 28 (06) :695-707

[8] STEREOSELECTIVE ORGANIC-REACTIONS - CATALYSTS FOR CARBONYL ADDITION PROCESSES [J].

EVANS, DA .

SCIENCE, 1988, 240 (4851) :420-426

[9] ENZYMES IN ORGANIC-SYNTHESIS [J].

JONES, JB .

TETRAHEDRON, 1986, 42 (13) :3351-3403

[10] ASYMMETRIC TRANSFORMATIONS CATALYZED BY ENZYMES IN ORGANIC-SOLVENTS [J].

KLIBANOV, AM .

ACCOUNTS OF CHEMICAL RESEARCH, 1990, 23 (04) :114-120