IMMUNOCHEMICAL TECHNIQUES FOR ENVIRONMENTAL-ANALYSIS .2. ANTIBODY-PRODUCTION AND IMMUNOASSAY DEVELOPMENT

被引:145
作者
MARCO, MP
GEE, S
HAMMOCK, BD
机构
[1] UNIV CALIF DAVIS,DEPT ENTOMOL,DAVIS,CA 95616
[2] UNIV CALIF DAVIS,DEPT ENVIRONM TOXICOL,DAVIS,CA 95616
关键词
D O I
10.1016/0165-9936(95)90920-I
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Antibody production is the key step of any immunochemical technique, The antibody determines to a large extent the specificity and sensitivity of the resulting immunochemical technique, These features may be modulated by judicious design of the immunogen and by rational immunoassay development, Criteria for hapten design and the steps involved in the obtention of antibodies and the development of competitive assays are described.
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页码:415 / 425
页数:11
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