STEREOSELECTIVE REDUCTION OF CODEINONE, THE PENULTIMATE ENZYMATIC STEP DURING MORPHINE BIOSYNTHESIS IN PAPAVER-SOMNIFERUM

被引：19

作者：

LENZ, R ^{[1
]}

ZENK, MH ^{[1
]}

机构：

[1] UNIV MUNICH,LEHRSTUHL PHARMACEUT BIOL,D-80333 MUNICH,GERMANY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 14期

关键词：

D O I：

10.1016/0040-4039(95)00278-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly substrate specific enzyme has been discovered and purified to homogeneity both from cell suspension cultures as well as from capsule tissue of Papaver somniferum which stereoselectively reduces (-)-codeinone to (-)-codeine and morphinone to morphine at the expense of NADPH.

引用

页码：2449 / 2452

页数：4

共 10 条

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