GENOTOXIC EFFECTS OF DELTAMETHRIN IN THE MOUSE BONE-MARROW MICRONUCLEUS ASSAY

被引：21

作者：

GANDHI, G ^{[1
]}

CHOWDHURY, JB ^{[1
]}

SAREEN, PK ^{[1
]}

DHILLON, VPS ^{[1
]}

机构：

[1] HARYANA AGR UNIV, DEPT GENET, HISAR 125004, HARYANA, INDIA

来源：

MUTATION RESEARCH LETTERS | 1995年 / 346卷 / 04期

关键词：

DELTAMETHRIN; BONE MARROW CELLS; MICRONUCLEI;

D O I：

10.1016/0165-7992(95)90036-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genotoxicity of deltamethrin was studied in Swiss albino male mice (five animals/group) using the bone marrow micronucleus assay. Deltamethrin (two i.p. injections, 30 h and 6 h before sample collection) was found to induce micronuclei at 162.5 and 300.0 mg/kg body weight. A lower dose (32.5 mg/kg body weight) failed to induce a significant increase in micronuclei over the control level.

引用

页码：203 / 206

页数：4

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