ENHANCING INVITRO ANTIBODY-PRODUCTION RATE PER CELL BY APPLYING MOUSE PERITONEAL FACTORS

被引：9

作者：

MIKAMI, T ^{[1
]}

MAKISHIMA, F ^{[1
]}

SUZUKI, E ^{[1
]}

机构：

[1] UNIV TOKYO,DEPT CHEM ENGN,7-3-1 HONGO,BUNKYO KU,TOKYO 113,JAPAN

来源：

BIOTECHNOLOGY LETTERS | 1991年 / 13卷 / 04期

关键词：

D O I：

10.1007/BF01041480

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Monoclonal antibody production rate per hybridoma cell was measured as much larger in mouse peritoneal cavity than in vitro culture. To identify factors enhancing antibody productivity per cell, a hybridoma was cultured in vitro with ascites and peritoneal exudate cells (PEC). Both the ascites and the PEC improved the productivity per cell in vitro. Each chromatograph-fraction of ascites was assayed for the enhancing activity.

引用

页码：255 / 260

页数：6

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