IFOSFAMIDE-INDUCED RENAL TUBULAR DEFECT

被引：2
作者：
VALDIVIESO, MJT
PEREZ, JL
MELERO, C
VIVANCO, JL
MULEY, R
VARA, J
机构：
[1] SOCIAL SECUR HOSP 12 OCTUBRE, DEPT PEDIAT HEMATOL ONCOL, MADRID, SPAIN
[2] SOCIAL SECUR HOSP 12 OCTUBRE, CHILD NEPHROL UNIT, MADRID, SPAIN
来源：
MEDICAL AND PEDIATRIC ONCOLOGY | 1994年 / 22卷 / 02期
关键词：
IFOSFAMIDE ADVERSE EFFECTS; KIDNEY-TUBULES-PROXIMAL; IFOSFAMIDE; RHABDOMYOSARCOMA;
D O I：
10.1002/mpo.2950220217
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We describe 2 cases of proximal tubular defects induced by the administration of ifosfamide at a dosage of 6 g/m2/course over 2 days in children with a diagnosis of malignant mesenchymal tumors. This adverse effect could be minimized dividing dosage of the drug. However at present it is not clear if divided doses are completely safe. (C) 1994 Wiley-Liss, Inc.
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收藏
页码：144 / 146
页数：3
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