MODEL-BUILDING IN STRUCTURE-ACTIVITY RELATIONSHIPS - RE-EXAMINATION OF ADRENERGIC BLOCKING ACTIVITY OF BETA-HALO-BETA-ARYLALKYLAMINES

被引：85

作者：

UNGER, SH ^{[1
]}

HANSCH, C ^{[1
]}

机构：

[1] POMONA COLL,DEPT CHEM,CLAREMONT,CA 91711

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1973年 / 16卷 / 07期

关键词：

D O I：

10.1021/jm00265a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：745 / 749

页数：5

共 17 条

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[4] DI-N-SUBSTITUTED 2-HALOGENOETHYLAMINES .6. NN--DIALKYL-(OR N-ALKYL)-2-ALKYL(OR ARYL OR ARYLALKYL) DERIVATIVES-SYNTHESIS, REACTIVITY, AND PHARMACOLOGY
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[5] DI-N-SUBSTITUTED 2-HALOGENOETHYLAMINES .7. NN-DI-ALKYL-2-1 - OR -2 -NAPHTHYL DERIVATIVES, AND SOME MISCELLANEOUS RELATED COMPOUNDS - SYNTHESIS, REACTIVITY, AND PHARMACOLOGY
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[6] SYNTHESIS REACTIVITY AND PHARMACOLOGICAL PROPERTIES OF SOME SUBSTITUTED NN-DIMETHYL-2-HALOGENO-2-PHENYLETHYLAMINES AND RELATED COMPOUNDS
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[7] Draper NR, 1966, APPLIED REGRESSION A
[8] GARNER GE, 1968, J PHARMACOL EXP THER, V162, P38
[9] STRUCTURE-ACTION RELATIONS IN N,N-DIMETHYL-2-HALOGENOPHENETHYLAMINES
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (02) : 103 - &
[10] REACTIONS OF BETA-SUBSTITUTED AMINES .2. NUCLEOPHILIC DISPLACEMENT REACTIONS ON 3-CHLORO-1-ETHYLPIPERIDINE
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[J]. TETRAHEDRON, 1972, 28 (02) : 239 - &

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