DRUG-RESISTANCE OF MYCOBACTERIUM-TUBERCULOSIS IN KARACHI, PAKISTAN

被引：11

作者：

KHAN, J

ISLAM, N

AJANEE, N

JAFRI, W

机构：

[1] Department of Medicine, Aga Khan University, Karachi, PO Box 3500, Stadium Road

来源：

TROPICAL DOCTOR | 1993年 / 23卷 / 01期

关键词：

D O I：

10.1177/004947559302300107

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We determined the primary and secondary resistance of isolates of M. tuberculosis to the standard anti-tuberculous drugs in Karachi (Pakistan). Primary resistance to one or more anti-tuberculous drugs was found in 17% of 123 isolates of M. tuberculosis (obtained from patients with no history of previous treatment for tuberculosis). Secondary resistance was found in 36% of 33 isolates (obtained from individuals who had received anti-tuberculous treatment in the past). The drug to which organisms were most commonly resistant was isoniazid (11% primary resistance, 30% secondary resistance). Fifteen per cent of isolates obtained from previously-studied patients showed secondary resistance to rifampicin. We discuss the importance of these findings for tuberculosis treatment and control.

引用

页码：13 / 14

页数：2

共 9 条

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