THE DETERMINATION OF CHARGE OF CATIONIC TC-99M-RADIOPHARMACEUTICALS

被引：2

作者：

RILEY, ALM ^{[1
]}

NOWOTNIK, DP ^{[1
]}

机构：

[1] AMERSHAM INT PLC,AMERSHAM HP7 9LL,BUCKS,ENGLAND

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1994年 / 17卷 / 03期

关键词：

D O I：

10.1080/10826079408013158

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Cation exchange HPLC methods for the determination of charge of cationic Tc-99m-complexes were developed, based on a method described previously for anions. Non-specific retention of lipophilic complexes was reduced by the addition of acetonitrile. The method was validated using a number of metal salts, and was used to confirm the charges on several lipophilic technetium cationic complexes.

引用

页码：533 / 548

页数：16

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