HIGH-FREQUENCY DELETION INVOLVING CLOSELY SPACED RIBOSOMAL-RNA GENE SETS IN STREPTOCOCCUS-THERMOPHILUS

被引：0

作者：

PEBAY, M ^{[1
]}

ROUSSEL, Y ^{[1
]}

SIMONET, JM ^{[1
]}

DECARIS, B ^{[1
]}

机构：

[1] UNIV NANCY 1,FAC SCI,GENET & MICROBIOL LAB,BP239,F-54506 VANDOEUVRE NANCY,FRANCE

来源：

FEMS MICROBIOLOGY LETTERS | 1992年 / 98卷 / 1-3期

关键词：

STREPTOCOCCUS-THERMOPHILUS; RRN LOCUS; GENETIC INSTABILITY; DELETION;

D O I：

10.1016/0378-1097(92)90130-G

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Homologous rDNA probes were used to study the number of rRNA genes in a five-generation genealogy of Streptococcus thermophilus CNRZ368. Whereas the CNRZ368 strain contained six rRNA loci, four independant mutants with five rrn loci were obtained. The deletion frequency was 5 x 10(-2). Molecular analysis provided identical hybridization patterns for all the deletion mutants. The deletion was shown to occur within the two close rRNA loci, rrnD and rrnE, probably due to a homologous recombination event and to give rise to a hybrid rrnD/E locus.

引用

页码：51 / 55

页数：5

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