IMPACT OF CLINICAL-TRIALS ON THE ADOPTION OF NEW DRUGS WITHIN A UNIVERSITY HOSPITAL

被引：19
作者：
DENIG, P
HAAIJER-RUSKAMP, FM
WESSELING, H
VERSLUIS, A
机构：
[1] UNIV GRONINGEN, DEPT PHARMACOL & CLIN PHARMACOL, GRONINGEN, NETHERLANDS
[2] UNIV HOSP GRONINGEN, DEPT PHARM, GRONINGEN, NETHERLANDS
来源：
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1991年 / 41卷 / 04期
关键词：
NEW DRUGS; PRESCRIBING PATTERN; CLINICAL TRIALS; SEMI-INNOVATIVE DRUGS; ADOPTION;
D O I：
10.1007/BF00314961
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
To assess the influence that clinical trials may have on the introduction of new drugs into prescribing routines, the adoption of drugs has been studied in a university hospital in the Netherlands. A significant relation was found between the testing of semi-innovative drugs in clinical trials in the hospital and the introduction of these drugs into general use in the same hospital. No such relationship was found for innovative drugs. Employment in clinical trials only affected the frequency of adoption of semi-innovative drugs. It did not influence the quantity of their use once they had been adopted. The idea that the stimulating effect of clinical trials on the adoption of semi-innovative drugs is only due to acceleration of the adoption process was not confirmed. These findings support the idea that clinical trials can lower the barriers for adoption of semi-innovative drugs.
引用
收藏
页码：325 / 328
页数：4
相关论文
共 9 条
  • [1] ABBING HDC, 1989, PHARM WEEKBLAD, V124, P343
  • [2] DUKES MNG, 1979, PHARM J, V223, P511
  • [3] THE DEFINED DAILY DOSE PER 100 BED-DAYS AS A UNIT OF COMPARISON AND A PARAMETER FOR STUDYING ANTI-MICROBIAL DRUG-USE IN A UNIVERSITY HOSPITAL - A RETROSPECTIVE STUDY OF THE EFFECTS OF GUIDELINES AND AUDIT ON ANTI-MICROBIAL DRUG-USE
    HEKSTER, YA
    VREE, TB
    GORIS, RJA
    BOEREMA, JBJ
    [J]. JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 1982, 7 (04): : 251 - 260
  • [4] PRESCRIBING HABITS OF PHYSICIANS - REVIEW OF STUDIES ON PRESCRIBING OF DRUGS
    MILLER, RR
    [J]. DRUG INTELLIGENCE & CLINICAL PHARMACY, 1973, 7 (12): : 557 - 564
  • [5] MILLER RR, 1973, DRUG INTELL CLIN PHA, V8, P81
  • [6] PLUMRIDGE R J, 1984, Australian Journal of Hospital Pharmacy, V14, P93
  • [7] Plumridge RJ, 1983, AUST J HOSP PHARM, V13, P44
  • [8] Plumridge RJ, 1983, AUST J HOSP PHARM, V13, P16
  • [9] 1988, DRUGDEX 1990, V63
1