CHIRAL DNA GYRASE INHIBITORS .2. ASYMMETRIC-SYNTHESIS AND BIOLOGICAL-ACTIVITY OF THE ENANTIOMERS OF 9-FLUORO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-2,3-DIHYDRO-H-7-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID (OFLOXACIN)

被引:101
作者
MITSCHER, LA [1 ]
SHARMA, PN [1 ]
CHU, DTW [1 ]
SHEN, LL [1 ]
PERNET, AG [1 ]
机构
[1] ABBOTT LABS,DIV ANTIINFECT RES,N CHICAGO,IL 60064
关键词
D O I
10.1021/jm00395a017
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
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页码:2283 / 2286
页数:4
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