A hexacationic coordination compound from Co(II) and a cationic ligand derived from 4,4 '-bipyridine: Synthesis, characterization and investigation for biological application

被引:6
作者
Abebe, Atakilt [1 ]
Tamiru, Getinet [1 ]
机构
[1] Bahir Dar Univ, Sci Coll, Chem Dept, Bahir Dar, Ethiopia
关键词
Hexapositively charged complex; cationic ligand; antibacterial acivity;
D O I
10.1080/23312009.2018.1564162
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A hexapositively charged tetrahedral geometry Co(II) complex was synthesized using a new positively charged ligand prepared quaternizing 4,4'-bipyridine by 1-bromobutane. It is characterized by spectrometry (H-1 NMR, ESI MS,Uv-Vis, ICP OES), carbon, hydrogen and nitrogen (CHN) elemental analysis, halide estimation and conductivity measurement. The complex showed significantly high molar conductivity value in water (640.83 S mol(-1) cm(2)). Its in vitro biological activities were tested on one gram-positive (Staphylococcus aureus) and one gram-negative (Klebsiella pneumoniae) bacteria. It was found active against both bacteria with improved and better activity against the latter.
引用
收藏
页数:9
相关论文
共 29 条
[1]   Synthesis of organic salts from 1,10-phenanthroline for biological applications [J].
Abebe, Atakilt ;
Atlabachew, Minaleshewa ;
Liyew, Misganaw ;
Ferede, Elsabet .
COGENT CHEMISTRY, 2018, 4 (01)
[2]   4,4-Bipyridinium ionic liquids exhibiting excellent solubility for metal salts: Potential solvents for electrodeposition [J].
Abebe, Atakilt ;
Admassie, Shimelis ;
Villar-Garcia, Ignacio J. ;
Chebude, Yonas .
INORGANIC CHEMISTRY COMMUNICATIONS, 2013, 29 :210-212
[3]  
Atkins P. W., 1994, PHYS CHEM, P834
[4]   Angle-dependent electronic effects in 4,4′-bipyridine-bridged Ru3 triangle and Ru4 square complexes [J].
Berben, Louise A. ;
Faia, Mary C. ;
Crawford, Nathan R. M. ;
Long, Jeffrey R. .
INORGANIC CHEMISTRY, 2006, 45 (16) :6378-6386
[5]   A H-1-NMR STUDY OF THE COMPLEX OF COBALT(II) WITH 2,5,8,11-TETRAMETHYL-2,5,8,11-TETRAAZADO IN AERATED AQUEOUS-SOLUTIONS [J].
BERTINI, I ;
MESSORI, L ;
GOLUB, G ;
COHEN, H ;
MEYERSTEIN, D .
INORGANICA CHIMICA ACTA, 1995, 235 (1-2) :5-8
[6]   Thermal behaviour and electrochemical properties of bis(trifluoromethanesulfonyl)amide and dodecatungstosilicate viologen dimers [J].
Bonchio, Marcella ;
Carraro, Mauro ;
Casella, Girolamo ;
Causin, Valerio ;
Rastrelli, Federico ;
Saielli, Giacomo .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 14 (08) :2710-2717
[7]   Hydrothermal syntheses, crystal structures, and magnetic properties of inorganic-organic hybrid vanadium selenites with zero- to three-dimensional structures:: (1,10-phenanthroline)2V2SeO7, (2,2′-bipyridine)VSeO4, (4,4′-bipyridine)V2Se2O8, and (4,4′-bipyridine)2V4Se3O15•H2O [J].
Dai, ZM ;
Shi, Z ;
Li, GH ;
Zhang, D ;
Fu, WS ;
Jin, HY ;
Xu, W ;
Feng, SH .
INORGANIC CHEMISTRY, 2003, 42 (23) :7396-7402
[8]   Cisplatin in cancer therapy: Molecular mechanisms of action [J].
Dasari, Shaloam ;
Tchounwou, Paul Bernard .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, 740 :364-378
[9]  
ELKALYOUBI SA, 2017, CHEM CENT J, V11, DOI DOI 10.1186/s13065-017-0351-8
[10]   BINDING OF DELTA-[RU(PHEN)(3)](2+) AND LAMBDA-[RU(PHEN)(3)](2+) TO [D(CGCGATCGCG)](2) STUDIED BY NMR [J].
ERIKSSON, M ;
LEIJON, M ;
HIORT, C ;
NORDEN, B ;
GRASLUND, A .
BIOCHEMISTRY, 1994, 33 (17) :5031-5040